Dr Rama Prasad

Potential Benefits of Ginger
Collected from: various researches and studies.
What it means: Indulge in ginger regularly.
  1. Ginger may benefit people at risk of many gastric diseases.
  2. Ginger shows anti-bacterial activities.
  3. Antimicrobial activity against Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli and Candida albicans.
  4. In another in vitro study,  ginger root extracts containing the gingerols inhibited the growth of H. pylori CagA+ strains.
  5. Since, helicobacter pylori (HP) is the primary etiological agent associated with dyspepsia, peptic ulcer disease and the development of gastric and colon cancer, some researchers believe that ginger and its extracts may benefit those suffered from or at risk of certain gastric diseases.
  6. Ginger has beneficial effects on nausea and vomiting of pregnant women according to a Sydney study.
  7. Ginger has antiemetic and anxiolytic activities. It may also help morning sickness.
  8. A recent single blind clinical trial study of 67 pregnant women showed that twice administration of 250 mg of ginger daily for four days could subside the incidents of vomiting.
  9. Animals treated with ginger root extract show decreased occupancy in the closed arm of the elevated plus maze suggesting the presence of anxiolytic principles. Ginger root extract also blocked lithium sulphate-induced conditioned place aversion indicating anti-emetic activity.
  10. Four double-blind randomized placebo-controlled trial suggests that ginger root is helpful for women suffering from morning sickness, nausea and vomiting of pregnancy.
  11. Its effects on nausea and vomiting during pregnancy is as good as vitamin B6. A study in Thailand of 138 women shows that there is no significant difference between ginger and vitamin B6 for the treatment of nausea and vomiting during pregnancy.
  12. Ginger may promote gastric intestinal motility
  13. Intake of ginger Root was found to enhance the transport of a charcoal meal in a study of mice.
  14. Ginger may offer benefits on reproduction.
  15. Ginger root extract was found to significantly increase in the relative weight of the testis, the serum testosterone level, testicular cholesterol level and epididymal a-glucosidase activity in a study of Wistar rats.
  16. Ginger has more than 50 antioxidants.
  17. Ginger root extract was shown to have antioxidant activities in a cell study. It may contain more 50 antioxidants.
  18. In one study, ginger rhizome (Zingiber officinale) was found to protect+ mice against radiation-induced lethality. The irradiation of animals resulted in a dose- dependent elevation in the lipid peroxidation. However, treatment of mice with ginger rhizome before irradiation caused a significant depletion in lipid peroxidation.
  19. Ginger may benefit people at risk of cardiovascular diseases.
  20. Ginger was found to inhibit 50% of a distinct development of atheroma in the aorta and coronary arteries of rabbits in a study. There was also distinct decrease in lipid peroxidation and enhancement of fibrinolytic activity in ginger treated animals. Authors suggested the protection was probably because of its free radical scavanging, prostaglandin inhibitory and fibri properties.
  21. Treatment with Z. officinale also caused a decrease in serum cholesterol, serum triglyceride and blood pressure in diabetic rats. The data suggest a potential antidiabetic activity of the juice of Z. officinale in type I diabetic rats, possibly involving 5-HT receptors.
  22. Ginger root extract was also demonstrated to reduce rat paw and skin edema.
  23. Ginger may benefit people at risk of osteoarthritis
  24. Ginger root extract can be used to treat osteoarthritis, as researchers found ginger decreased the productin of inflammatory mediators in sow osteoarthrotic cartilage explants.
  25. Ginger may benefit people at risk of cancer
  26. Adding ginger root extract into drinking water was found to reduce the risk of mammary tumor in study of mice.
  27. Dietary ginger constituents, galanals A and B, are found to be potent apoptosis inducers in Human T lymphoma Jurkat cells
  28. In addition, the rhizome of ginger contains pungent vanillyl ketones, including [6]-gingerol and [6]-paradol, and has been reported to possess a strong anti-inflammatory activity. These pungent substances have a vanilloid structure found in other chemopreventive phytochemicals, including curcumin.
  29. Surh YJ et al, Seoul National University, found anti-tumor properties of these compounds. Topical application of [6]-gingerol or [6]-paradol 30 min prior to 12-O-tetradecanoyl-phorbol-13- acetate (TPA) attenuated the skin papillomagenesis initiated by 7,12 dimethylbenz[a] anthracene in female ICR mice.
  30. Reactive nitrogen species (RNS), such as nitric oxide (NO) and its derivatives, e.g. peroxynitrite (ONOO-), have been proposed as being able to influence signal transduction and cause DNA damage, contributing to carcinogenic processes. While, [6]-gingerol is found to be a potent inhibitor of NO synthesis and also an effective protector against peroxynitrite- mediated damage.
  31. While, other researchers found that 6-gingerol induced apoptosis in
  32. HL-60 cells. However, this activity was not related its anti-oxidative activity.
  33. Ginger may benefit people at risk of diabetes
  34. Antidiabetic and hypoglycemic drugs enhance adipocyte differentiation of 3T3-L1 preadipocytes. Study demonstrates gingerol-treated cells increase insulin-sensitive glucose uptake. Thus, ginger may enhance the insulin-sensitivity, and improve chronic disease, such as diabetes.
  35. In a study with diabetic rats, treatment with Z. officinale (i.e. ginger) produced a significant increase in insulin levels and a decrease in fasting glucose levels in diabetic rats. In an oral glucose tolerance test, treatment with Z. officinale was found to decrease significantly the area under the curve (i.e. the extent of absorption) of glucose and to increase the area under the curve of insulin in STZ-diabetic rats.
  36. Acute hyperglycemia evokes gastric slow wave dysrhythmias via endogenous prostaglandin generation. Ginger exhibits slow wave antiarrhythmic effects.
  37. Ginger may benefit people at risk of Alzheimer’s disease An important feature for Alzheimer's disease is neuritic plaque. Neuritic plaques are extracellular deposits of beta-amyloid peptides (Abeta). In the central nervous system neuritic plaques are surrounded by activated microglial cells expressing pro-inflammatory cytokines, chemokines, and neurotoxic mediators. Long-term activation of microglial cells is suspected to contribute to the neuron loss in Alzheimer's  disease.
  38. Ginger can inhibit the activation of human monocytic THP-1 cells by different pro-inflammatory stimuli and reduce the expression of a wide range of inflammation-related genes in these microglial-like cells. Consequently, ginger extract may be useful in delaying the onset and the progression of neurodegenerative disorders involving chronically activated microglial cells in the central nervous system.
  39. Ginger Side Effects, Interactions and Warnings
  40. Avoid in heartburns, in overheated and bleeding conditions,
  41. Ginger may interact with surgical medications including anesthesia, leading to arrhythmias, poor wound healing, bleeding, photosensitivity reaction, and prolonged sedation. [28] Ginger has may also interact with certain anticoagulants and analgesics to cause bleeding.

Read more about ginger here and here
and have your ginger tea quickly...